Biological Discovery Research
488 open positions
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Sr. Principal Scientist / Director, DMPK & Bioanalytical Sciences FlagshippioneeringincAlltrna $179k–$179k2mo Leads DMPK and bioanalytical strategy across nonclinical and clinical programs for tRNA therapeutics, including PK study design, method development, and translational biomarker strategy.
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Scientist I, Functional Bioassay & High-Throughput Screening GeneratebiomedicinesSomerville, MA $102k–$102k2mo Design, optimize, and execute biochemical and cell-based high-throughput screening (HTS) assays to generate functional data for AI/ML-enabled protein therapeutic design.
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Genomics Scientist IdexxWestbrook, ME $90k–$90k2mo Design, develop, and validate PCR-based molecular assays to support pet health diagnostics and translate experimental data into scientific insights.
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Staff Scientist RochesterKornberg Medical Research Building $0k–$0k2mo Investigate mechanisms dictating DNA fate in bacterial cells and develop microbial genome engineering approaches using phage recombinase-mediated integration.
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Genomics Sr Staff Scientist Stanfordmedicine3375 Hillview - Clinical - PALO ALTO $138k–$138k2mo Interpret clinical genetic and genomic test results by prioritizing variants from sequencing data and drafting clinical reports for patient care.
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Principal/Senior Scientist, PK/PD Assays NewLimitSouth San Francisco $155k–$155k2mo Lead the design, development, and qualification of pharmacokinetic (PK) and pharmacodynamic (PD) assays to characterize the biodistribution and biological activity of mRNA-LNP medicines in preclinical and IND-enabling studies.
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Senior Scientist, R&D Design Transfer & Product Development NateraUS - TX - Austin $116k–$116k2mo Lead the transition of In Vitro Diagnostic (IVD) Next-Generation Sequencing (NGS) assays from R&D to Operations, ensuring compliance with regulatory and quality standards.
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Scientist 3- Translational Medicine (Multiple Sclerosis & TR focused) RocheSouth San Francisco $100k–$100k2mo Scientist integrating human clinical biospecimens with advanced molecular profiling and omics technologies to drive biomarker discovery and disease biology insights for Multiple Sclerosis clinical development.
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Principal Scientist II - Pharmacology NovartisCambridge (USA) $126k–$234k2mo Lead in vivo anti-tumor efficacy and PK/PD studies using CDX, PDX, and syngeneic models to evaluate novel cancer therapies and inform clinical development.
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Scientist - Cancer Modeling UmiamiMiami, FL 2mo Lead the Cancer Modeling Shared Resource to provide state-of-the-art in vivo and tissue-based research services, including disease modeling, noninvasive imaging, and histopathology, supporting translational cancer research.
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テクニカルアプリケーションスペシャリスト / Technical Application Specialist (CSD) ThermofisherTokyo, Japan 2mo Provide technical consultation and support for Next-Generation Sequencing (NGS) products, leading customer problem-solving and research advancement.
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Senior Scientist - Neurology WustlWashington University Medical Campus $63k–$63k2mo Spearhead research projects exploring cellular senescence, tau biology, and their roles in neurodegenerative diseases.
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Scientist I, De Novo Discovery and Screening ParabilismedCambridge $110k–$110k2mo Designing and executing phage and mRNA display high-throughput screening campaigns to discover novel binders against challenging protein targets for next-generation therapeutics.
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Senior/Principal Scientist, Small Molecule Therapeutics LilasciencesAlewife, Cambridge, MA $148k–$148k2mo Lead early hit identification efforts using DNA-encoded libraries (DEL) and complementary screening technologies to discover and validate novel chemical matter for small molecule therapeutics.
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Senior Scientist I, Cell Therapy Discovery AstraZenecaShanghai - Guilin Road 2mo Lead CAR construct design, T-cell engineering, and in vitro functional characterization to advance cell therapy programs from discovery toward translation.
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Senior Scientist R&D TempusChicago, US $94k–$94k2mo Design and development of molecular assays for IVD & CDx programs, leading validation studies and ensuring regulatory compliance for FDA submissions.
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Senior Scientist, Mechanistic Pharmacology CslEMEA, CH, Schlieren, CSL Behring 2mo Developing and optimizing advanced cellular and complex in vitro models (iPSC, co-culture, organoids, organ-on-a-chip) for cardiovascular and renal indications to support translational research and target validation.
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Senior Principal Scientist, Cancer Immunology, Discovery Biology, Oncology Thematic Research Center BristolmyerssquibbSeattle 400 Dexter - WA - US $174k–$174k2mo Lead matrixed T cell engager (TCE) and cancer immunology discovery teams from target concept to IND, leveraging proprietary technologies to identify and validate novel therapeutic approaches for refractory tumors.
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Mass Spectrometry Scientist Convergent ResearchWatertown, MA 2mo Maintain mass spectrometers and execute hypothesis-driven proteomic experiments to investigate disease mechanisms like Alzheimer's.
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Sr Associate Scientist, Metabolic & Muscle Diseases RegeneronTARRYTOWN $80k–$80k2mo Central histological resource providing expert tissue processing, staining, and image analysis services to Obesity, Metabolism and Muscle Diseases research programs.
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Wetlab Protocol Specialist - Freelance AI Trainer Project AgencyRemote $0k–$0k3mo You will converse with advanced language models on practical lab scenarios and theoretical protocol questions to verify factual accuracy, capture error traces, and suggest improvements to prompt engineering.
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Senior Scientist I, Cell Line Development AbbVieSouth San Francisco, CA, us 3mo Designing and optimizing CHO cell line platforms to increase recombinant antibody titers for biologics manufacturing.
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Production Sequencing Lead Basecamp-ResearchLondon 3mo Operational lead for the Trillion Gene Atlas, owning the sample-to-sequence pipeline end-to-end from DNA extraction through sequencing dispatch to drive throughput and translate R&D into production.
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Principal Scientist, Bioanalytical & Molecular Assays ModernaTXOxford - England 3mo Lead the design, development, validation, and deployment of advanced molecular assays (RT-qPCR, dPCR, NGS) to generate high-quality clinical data supporting decision-making across multiple therapeutic programs from discovery through Phase 3 clinical…
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Scientist - Yen Lab/TGEn Group (Hematopoietic Stem Cell, Genome Editing) StjudeMemphis, TN $86k–$86k3mo Develop genome editing strategies for human hematopoietic stem cells (HSC) to treat sickle cell disease and other hematological diseases, advancing from pre-clinical to IND-enabling studies.
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Staff Scientist, Surface Chemistry ElementbiosciencesSan Diego - Headquarters $158k–$158k3mo Lead scientific development of surface chemistry solutions for next-generation sequencing and multiomics applications, translating research into manufacturable products.
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Senior Scientist, Cardiac Modeling InsitroSouth San Francisco, CA $156k–$156k3mo Develop and apply iPSC-derived cardiomyocyte (iPSC-CM) models to study genetic and molecular underpinnings of cardiovascular disease, generating datasets for ML-driven drug discovery.
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Flow Cytometry Systems Engineer NomicGreater Boston 3mo Internal subject-matter expert for commercial flow cytometers, ensuring robust, reproducible cytometry workflows for nELISA readout across internal operations, R&D, and customer deployments.
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Scientist or R&D engineer – Strain Development RISE Research Institutes of Sweden ABÖrnsköldsvik, Sweden 3mo Developing microbial strains for sustainable biobased solutions including biochemicals, biofuels, biomaterials, proteins, enzymes, and food/feed.
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Process Development Senior Research Associate / Associate Scientist NanopathincNanopath HQ 3mo Developing, optimizing, and scaling workflows for a first-in-class in vitro diagnostics platform to replace lengthy molecular testing with rapid, high-quality diagnostics.
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Scientist, Biological Sciences AltoslabsSan Diego, California $116k–$116k3mo Conducting basic science, pre-clinical, and clinical-stage research to unravel the mechanistic basis of cell programming for health and rejuvenation.
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Director, Screening and High Content Analysis QuickenloansDetroit, MI 3mo Lead the development and execution of a high-content screening platform using organoid and cell-based models to drive target discovery and therapeutic development for NF1 and related neurological disorders.
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R&D - Intrepide-Principal Scientist I, Biologics Discovery & Innovation - SZ SanofiSuzhou (Jiangsu) 3mo Lead global R&D projects for biologics discovery, engineering, and technology platforms in oncology, immunology, ophthalmology, or CNS, operating in internal–CRO hybrid models.
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