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Discovery Immunology Principal Research Scientist

Seattle, WA💼 Full-time💰 $140,000–$140,000🗓 2026-09-01 → 2026-09-26

Core

Lead discovery immunology programs for autoimmune diseases, focusing on target identification, validation, and mechanism-of-action studies.

Role type

Principal Research Scientist (Discovery Immunology)

Builds

Early-stage drug discovery programs and therapeutic targets for autoimmune conditions

Domain

Biotechnology / Immunology / Autoimmune Diseases

Deliverable

production ML models | product features | dashboards & analysis | research

Required skills

Immunology assay development, cell-based testing, mechanistic studies, immune-cell profiling, flow cytometry, multiparameter functional analysis, molecular and biochemical analyses, target validation, pathway interrogation, preclinical disease model development, systems-immunology approaches

Preferred skills

Immune–stromal cell or organoid co-cultures, single-cell analysis, genomic analysis, proteomic analysis, bioinformatics approaches

Technologies

Flow cytometry, single-cell platforms, genomic tools, proteomic tools

Responsibilities

Lead discovery immunology programs from target identification through mechanism-of-action studies; Design, oversee, and interpret in vitro, ex vivo, and in vivo studies; Develop disease-relevant models and translational strategies; Collaborate with chemistry, computational biology, and project management to guide programs; Mentor scientists and foster scientific excellence; Track emerging science and contribute to publications and presentations

Seniority

Principal, scientific leadership & strategy

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