Discovery Immunology Principal Research Scientist
Core
Lead discovery immunology programs for autoimmune diseases, focusing on target identification, validation, and mechanism-of-action studies.
Role type
Principal Research Scientist (Discovery Immunology)
Builds
Early-stage drug discovery programs for autoimmune and inflammatory diseases
Domain
Biotechnology / Immunology / Autoimmune Diseases
Required skills
Immunology assay development, cell-based testing, mechanistic studies, immune-cell profiling, flow cytometry, multiparameter functional analysis, molecular and biochemical analyses, target validation, pathway interrogation, preclinical disease models, hypothesis-driven study design, scientific leadership, mentoring
Preferred skills
Immune–stromal cell or organoid co-cultures, single-cell and genomic approaches, proteomic and systems-immunology approaches, bioinformatics
Technologies
Flow cytometry, single-cell analysis, genomic analysis, proteomic analysis, bioinformatics tools
Responsibilities
Lead discovery immunology programs from target identification through mechanism-of-action studies; Design, oversee, and interpret in vitro, ex vivo, and in vivo studies; Develop disease-relevant models and translational strategies; Collaborate with cross-functional teams to guide programs; Mentor scientists and foster scientific excellence; Track emerging science and contribute to publications and presentations
Seniority
Principal, scientific leadership & mentorship