Senior Scientist / Scientist, In Vivo Pharmacology
Core
Design and execute in vivo pharmacology studies (PK/PD, efficacy, dose-response) to evaluate epigenetic reprogramming therapeutics in animal models.
Role type
Senior Scientist / Scientist, In Vivo Pharmacology
Builds
Pre-clinical data packages for drug development programs
Domain
Biotechnology / Epigenetic Aging / Nonclinical Pharmacology
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
in vivo study design, PK/PD analysis, animal model development, CRO/vendor management, regulatory study design, technical mentorship
Preferred skills
liver biology, nucleic acid/viral vector delivery, GLP/IND-enabling study design, single cell genomics
Technologies
rodent models, CRO platforms
Responsibilities
Design, execute, and interpret in vivo pharmacology studies across multiple disease models; Collaborate with therapeutic area teams to evaluate epigenetic reprogramming payloads; Develop and refine animal models of aging and age-related disease; Oversee study design, protocol development, and CRO/vendor relationships; Analyze and interpret in vivo data to drive pre-clinical decision making; Contribute to regulatory-enabling study design and documentation.
Seniority
Senior Scientist (8+ years) / Scientist (5+ years), hands-on IC with mentorship