Sr. Scientist, Biologics Engineering
Core
Design, engineer, and express recombinant proteins and antibodies (including bispecifics and fusions) using transient and stable expression platforms to advance biologic therapeutics.
Role type
Senior Scientist, Biologics Engineering (hands-on IC with project oversight)
Builds
Recombinant protein therapeutics, stable CHO cell lines, and antibody discovery assets
Domain
Biotechnology / Biologics / Protein Engineering
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
Molecular biology, protein engineering, mammalian cell culture, transfection, expression workflows, protein purification, in vitro analytical characterization (SEC, Octet), flow cytometry (FACS), CRO management
Preferred skills
Antibody-oligonucleotide conjugates, lentiviral transduction, gene editing, mass spectrometry-based characterization
Responsibilities
Design and execute experiments for antibody discovery and lead optimization; manage external protein production activities at CROs; characterize antibody binding and cell-surface target engagement; present findings at team meetings
Seniority
Senior, hands-on IC with project oversight