Optics / Microscopy Principal Scientist
Core
Design and develop custom optical instruments and functional imaging platforms to accelerate drug discovery pipelines.
Role type
Principal Scientist (Optics/Microscopy)
Builds
Custom optical instruments and automated imaging systems for drug discovery
Domain
Biotechnology / Drug Discovery / Optical Engineering
Deliverable
production ML models | product features | physical/clinical work
Required skills
Optical design (ray tracing, ABCD matrices, Gaussian beams), Microscopy modalities (confocal, light sheet, super-resolution, two-photon), Instrument specification, Automation/High-throughput screening, Data analysis programming, Biological assay optimization, Team leadership
Preferred skills
Experience with voltage or calcium imaging, Hands-on experience with optical table setups
Technologies
Optical table setups, Widefield fluorescence, Confocal microscopy, Light sheet microscopy, Super-resolution microscopy, Two-photon microscopy
Responsibilities
Collaborate with cross-disciplinary teams to identify opportunities for custom instrumentation, Design and build prototype optical instruments, Conduct proof-of-concept experiments and optimize assays, Work with engineers to build robust production-ready instruments, Align stakeholders and propose new projects to senior leaders, Supervise and mentor junior researchers
Seniority
Principal, hands-on IC with leadership potential
