Senior Principal Scientist -Bioanalytical Assay- Cell Therapy
Core
Scientific leader defining bioanalytical strategy for cell therapy product development, focusing on characterizing in vivo fate of therapeutic cells to inform regulatory and portfolio decisions.
Role type
Senior Principal Scientist (Bioanalytical Strategy)
Builds
Integrated bioanalytical strategies and evidence packages for cell therapy programs
Domain
Biopharmaceuticals / Cell Therapy / Bioanalytical Sciences
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
Bioanalytical strategy definition, Cell therapy development expertise, In vivo cell fate characterization, Flow cytometry, Molecular assays (qPCR/ddPCR), Ligand-binding assays, Functional bioassays, Biomarker assays, Multiomic approaches, Cross-functional leadership, Scientific publication record
Preferred skills
Data integration across modalities, Harmonized assay strategies, AI-enabled data interpretation
Technologies
Flow cytometry, qPCR, ddPCR, Multiomic platforms
Responsibilities
Define and drive bioanalytical strategy for the Cell Therapy portfolio; Identify and prioritize scientific questions regarding cellular expansion, persistence, trafficking, and immunogenicity; Partner with project leads to develop fit-for-purpose analytical approaches; Build strategic partnerships across Research, Clinical, CMC, and Regulatory teams; Harmonize scientific approaches and establish portfolio-wide best practices; Represent Bioanalytical Sciences on cross-functional governance teams; Mentor scientists and foster scientific excellence.
Seniority
Principal, strategy & mentorship