Scientist – Erythroid Biology
Core
Design and execute in vitro and ex vivo assays to evaluate siRNA delivery and function, develop human primary cell-based systems, and support target validation for siRNA therapeutics.
Role type
Scientist (Erythroid Biology / siRNA Therapeutics)
Builds
siRNA therapeutics and delivery systems
Domain
Biotechnology / Oncology / Hematology
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
siRNA delivery and functional assays, Erythroid biology and hematopoiesis, Flow cytometry (multi-color), Cell-based functional assays, gene expression analysis (qPCR, RNA assays), target engagement assays
Preferred skills
Hemoglobinopathies, conjugated delivery systems, CRISPR or gene editing
Technologies
siRNA, Flow cytometry, qPCR, CRISPR
Responsibilities
Design and execute in vitro and ex vivo assays to evaluate siRNA delivery and function; Develop human primary cell-based systems; Support target validation and mechanism-of-action studies for siRNA therapeutics; Establish and optimize Flow cytometry panels, qPCR / RNA-based readouts; Contribute to IND-enabling studies and data packages; Collaborate with Delivery/chemistry teams, Translational and biomarker teams
Seniority
Mid-Senior, hands-on IC
