Scientist 3 – Translational Medicine – OMNI – Inflammatory Bowel Disease
Core
Design and execute translational research studies in Inflammatory Bowel Disease (IBD) using human biospecimens and high-dimensional omics to discover biomarkers and validate therapeutic mechanisms.
Role type
Senior IC translational medicine scientist (wet-lab + data analysis)
Builds
Novel biomarker strategies, human-relevant disease models, and patient stratification approaches for IBD therapeutics
Domain
Biopharmaceuticals / Immunology / Inflammatory Bowel Disease
Required skills
Immunology, Cell/Molecular Biology, Mucosal Biology, Flow cytometry, Multiplex immunoassays, ELISA, Histology, scRNA-seq, CITE-seq, R, Python
Preferred skills
Primary cell isolation from human intestinal tissue, 3D organoid cultures, Microphysiological systems (gut-on-a-chip), Spatial transcriptomics, Proteomics
Technologies
scRNA-seq, CITE-seq, Spatial transcriptomics, Proteomics, R, Python
Responsibilities
Design and perform experimental studies using patient-derived human biospecimens; Establish and execute complex human-relevant model systems (organoids, co-cultures); Develop and execute custom assays (multiplex immunoassays, ELISA, flow cytometry, histology); Analyze and integrate high-dimensional datasets (scRNA-seq, CITE-seq, spatial transcriptomics, proteomics); Support clinical biomarker research strategies by translating lab findings into actionable insights; Evaluate and implement emerging technologies and experimental platforms
Seniority
Senior, hands-on IC
