Senior Scientist, Analytical Chemistry
Core
Analytical characterization and formulation of oligonucleotides to support drug discovery research, ensuring identity, purity, and stability for in vitro and in vivo experiments.
Role type
Senior Scientist, Analytical Chemistry
Builds
Research samples and analytical data for oligonucleotide therapeutics
Domain
Biotechnology / Drug Discovery / Oligonucleotide Chemistry
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
HPLC, mass spectrometry, oligonucleotide laboratory techniques, process design and implementation, endotoxin analysis, sample tracking system management
Preferred skills
oligonucleotide therapeutics analytics, in vitro/in vivo assay understanding, bioanalysis, GxP methods
Technologies
HPLC, LCMS, mass spectrometry
Responsibilities
Maintain workflows for analytical characterization of oligonucleotides at CROs; develop and implement plans for LCMS system installation; act as key opinion leader for oligonucleotide characterization; develop analytical methods for chemical and metabolic stability; generate Certificate of Analysis reports; perform formulation processes for research samples; develop and maintain a sample tracking system
Seniority
Senior, hands-on IC
