Discovery Postdoctoral Fellow, Target Identification and Mechanistic Biology for Antimalarial Drug Discovery
Core
Develop and apply innovative target-identification and interactomics approaches to uncover biological pathways underlying parasite survival and drug response for antimalarial compounds.
Role type
Postdoctoral Research Fellow (Target Identification & Mechanistic Biology)
Builds
Fundamental discoveries in parasite biology and new opportunities for antimalarial drug discovery
Domain
Biomedical research / Antimalarial drug discovery / Malaria biology
Deliverable
Research
Required skills
Phage display technology, Molecular biology techniques (cloning, recombinant DNA, library construction, protein expression), Biochemical and structural validation methods, Cell-based assays
Preferred skills
Protein-protein interaction technologies (affinity purification, immunoprecipitation, proximity labeling), Mass spectrometry-based proteomics, Computational analysis of biological datasets
Technologies
T7 phage display, Mass spectrometry, Next-generation sequencing
Responsibilities
Design and characterize phage display libraries for Plasmodium falciparum proteome, Develop and optimize phage display screening workflows, Execute biochemical, structural, and cell-based validation studies, Collaborate across malaria biology, proteomics, and computational biology disciplines, Publish scientific manuscripts in high-impact journals
Seniority
Postdoctoral Fellow (early-career scientist immediately following PhD)
