CareerPlanGet AI match score →

Scientist, Target Discovery & Validation

United States💼 Full-time💰 $110,400–$110,400🗓 2026-05-11 → 2026-07-20

Core

Identify novel drug targets in various indications and tissues, and lead preclinical proof of concept studies to validate target feasibility.

Role type

Scientist, Target Discovery & Validation

Builds

Drug candidates from idea to clinic

Domain

Biopharmaceuticals / RNA therapeutics / Human genetics

Deliverable

production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work

Required skills

Mammalian disease models, human genetics, assay development, project management, CRO management, mentoring

Preferred skills

Postdoc experience, disease biology focus, publication record, human genetics for mechanism

Technologies

Animal models, in vitro disease models, genomic approaches

Responsibilities

Identify promising novel targets with genetics/omics/clinical teams; Design and execute proof of concept experiments in animal and in vitro models; Design studies, coordinate activities, and lead from the bench; Oversee lead discovery activities for drug candidate selection; Develop assays to monitor target engagement/pharmacodynamic responses; Manage relationships with CROs and academic collaborators; Mentor junior scientists.

Seniority

Mid-level Scientist (PhD + 0-2 years)

Sourced via eightfold · Listed on CareerPlan, which tracks 70,000+ jobs from 20+ sources.
Apply on alnylam ↗