Senior Associate Scientist, Medicinal Chemistry
Core
Developing and supporting novel chemistry solutions for the advancement of an RNAi platform using strong organic synthesis skills.
Role type
Senior Associate Scientist, Medicinal Chemistry
Builds
Novel chemical modifications and delivery modalities for siRNA
Domain
Biopharmaceuticals / RNAi therapeutics
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
Organic synthesis, multi-step synthesis, purification, structural analysis, LC/MS/NMR data interpretation, small molecule characterization
Preferred skills
Understanding of reaction mechanisms and chemical reactivity, flexibility to apply knowledge to new areas of study
Technologies
NMR, HPLC, LCMS
Responsibilities
Develop and execute syntheses of novel chemical modifications and delivery modalities for siRNA; Perform multi-step synthesis, purification, and structural analysis of intermediate compounds; Synthesize organic building blocks for RNA delivery; Troubleshoot and maintain critical instrumentation (NMR, HPLC, LCMS); Analyze and organize data to prepare experimental reports
Seniority
Mid-level (2-3 years experience)