Associate Scientist II, Oligonucleotide Synthesis
Core
Synthesize, purify, and analyze chemically modified oligonucleotides to support RNAi-based medicine development.
Role type
Associate Scientist II, Oligonucleotide Synthesis
Builds
Chemically modified oligonucleotides for RNAi therapeutics
Domain
Biopharmaceuticals / RNAi drug development
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
solid-phase synthesis (SPS), HPLC, LC-MS, UV-Vis, process optimization, troubleshooting, laboratory automation familiarity
Preferred skills
industrial experience, deep understanding of SPS mechanisms
Technologies
HPLC, LC-MS, UV-Vis, liquid handlers
Responsibilities
Design and execute high-throughput synthesis of modified oligonucleotides using automated platforms; Carry out downstream purification and analytical characterization; Optimize and develop new synthetic methods; Troubleshoot synthetic/process issues; Analyze data to improve yield and purity; Maintain lab equipment and documentation
Seniority
Mid-level, hands-on IC