Sr. Scientist, Primary Pharmacology
Core
Design and execute in vitro pharmacology assays to support small molecule hit identification, lead discovery, and optimization for internal medicine disease indications.
Role type
Senior Scientist, Primary Pharmacology
Builds
Small molecule drug discovery projects
Domain
Pharmaceutical R&D, Drug Discovery
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
in vitro assay development and execution, protein biochemistry, mechanistic pharmacology, target biology, data analysis, experimental design
Preferred skills
experience with membrane receptors/enzymes/transcription factors, molecular biology techniques (RT-qPCR, transfection, western blotting), cardiovascular and metabolic signaling pathways
Technologies
HTRF, ELISA FP, BRET, radioligand binding
Responsibilities
Design and execute in vitro assays for diverse protein targets; investigate target binding and engagement; analyze data and write reports; collaborate with cross-disciplinary teams (chemistry, structural biology, computational biology)
Seniority
Senior, hands-on IC