Scientist I, Functional Bioassay & High-Throughput Screening
Core
Design, optimize, and execute biochemical and cell-based high-throughput screening (HTS) assays to generate functional data for AI/ML-enabled protein therapeutic design.
Role type
Scientist I, Functional Bioassay & High-Throughput Screening
Builds
Functional assay data and experimental workflows for therapeutic discovery programs
Domain
Biotechnology / Protein Therapeutics / Drug Discovery
Deliverable
production ML models
Required skills
Cell-based and biochemical assay design, mammalian cell culture, plate-based assay workflows, ELISA, HTRF, AlphaLISA, luminescence/fluorescence assays, flow cytometry, data analysis (GraphPad Prism, ScreenWorks, Harmony, iQue Forecyt, Spotfire), laboratory troubleshooting, electronic laboratory notebook management
Preferred skills
Ion channel assay experience, GPCR assay experience, ADC assay experience, primary cell or engineered cell line work, lab automation system experience (HighRes, Beckman Biomek, Hamilton, EL406, Multidrop)
Responsibilities
Design and implement HTS-compatible biochemical and cell-based assays; execute plate-based HTS campaigns and analyze results; troubleshoot assay performance and instrumentation; maintain accurate records in electronic laboratory notebooks; communicate findings to support AI/ML-enabled design cycles; collaborate with cross-functional teams including Data Science and Automation
Seniority
Early-career Scientist I