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Senior Scientist II, Rheumatology

Cambridge, MA, us💼 Full-time🗓 2026-07-13 → 2026-07-31

Core

Preclinical drug discovery for Rheumatoid Arthritis and Psoriatic Arthritis, focusing on target validation, mechanism-of-action studies, and translational research.

Role type

Senior Scientist II, preclinical immunology

Builds

Preclinical data packages and novel therapeutic strategies for rheumatological autoimmune diseases

Domain

Pharmaceutical R&D, Immunology, Inflammation Biology

Deliverable

production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work

Required skills

in vivo disease models, in vitro pharmacology, PK/PD relationships, assay development, mechanism-of-action studies, flow cytometry, PCR/gene expression analysis, protein and cytokine quantification, histopathology

Preferred skills

preclinical pharmacology, pharmaceutical or biotechnology industry experience

Technologies

flow cytometry, PCR, gene expression analysis, protein quantification, cytokine quantification, histopathology

Responsibilities

Set Rheumatology strategy for pipeline programs and contribute to target evaluation and model development; Drive in vitro and in vivo pharmacology for drug candidates; Develop acute and/or chronic murine models of inflammation; Apply immunological techniques to generate functional readouts; Design experiments, analyze data, and present findings at scientific forums and conferences; Author and review technical reports, protocols, and key scientific documents.

Seniority

Senior, hands-on IC

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