Scientist/Senior Scientist, Immunology
Core
Lead discovery-to-preclinical research in inflammatory and autoimmune diseases, focusing on T cell and regulatory T cell (Treg) biology to support epigenetic reprogramming interventions.
Role type
Senior Scientist, Immunology
Builds
Preclinical efficacy, safety, and mechanism-of-action studies for lead selection in aged T cells.
Domain
Biotechnology / Immunology / Epigenetic Aging
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
multi-parameter flow cytometry, in vivo autoimmune/inflammatory disease models, primary immune cell isolation, ex vivo culture, Treg functional assays, IND-supporting study reports
Preferred skills
pooled in vitro/in vivo screening (CRISPR fitness, Perturb-seq, CROP-seq), rheumatoid arthritis/colitis models, CRO management, basic computational tools (Python, R)
Technologies
Python, R
Responsibilities
Design and implement in vitro screening assays for T cells and Tregs; Design and lead in vivo and in vitro immunology studies; Contribute expertise in inflammatory/autoimmune disease biology to experimental design; Author study reports and regulatory documentation; Mentor junior scientists; Present data and scientific recommendations to leadership
Seniority
Senior, hands-on IC with mentorship