Senior Research Associate, DNA Encoded Library Technology ~ Contract
Core
Design, validate, and construct DNA-encoded libraries (DELs) to support targeted protein degradation drug discovery.
Role type
Senior Research Associate (Contract), Discovery Chemistry
Builds
Novel DEL library builds and new DNA-compatible chemical transformations
Domain
Biopharmaceuticals / Targeted Protein Degradation / DNA-Encoded Library Technology
Required skills
synthetic organic chemistry, DNA-encoded library synthesis, LCMS/HPLC analysis and purification, library build design, cross-functional collaboration
Preferred skills
drug design and SAR optimization, high-throughput analytical systems, molecular biology tools (PCR, qPCR, Western Blot), platform automation
Technologies
LCMS, HPLC, PCR, qPCR, Western Blot
Responsibilities
Design and validate novel DEL library builds; Develop new DNA-compatible chemical transformations; Construct DEL libraries; Work with external partners for synthesis and hit follow-up; Engage in cross-functional discussions on screening and data analysis; Contribute to platform automation; Present results and document workflows
Seniority
Senior, hands-on IC
