Scientist I, ASO Process Development and Manufacturing
Core
Design and develop robust manufacturing processes for the synthesis of oligonucleotides (ASOs) to support clinical and commercial therapeutics.
Role type
Scientist I, ASO Process Development and Manufacturing
Builds
Pilot-scale ASO syntheses and optimized synthesis processes
Domain
Biotechnology / Oligonucleotide Chemical Development
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
Synthetic organic chemistry, reaction mechanisms, experimental design, data interpretation, CMC documentation
Preferred skills
Nucleoside chemistry, oligonucleotide synthesis, synthetic process R&D
Technologies
Laboratory synthesis equipment, analytical instrumentation
Responsibilities
Design and conduct laboratory experiments to optimize synthesis processes, Perform ASO pilot-scale syntheses to support preclinical studies, Author CMC sections of INDs
Seniority
Junior, hands-on IC