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Principal Scientist, Biophysicist

LaJolla/SD💼 Full-time💰 $108,500–$108,500🗓 2026-07-15 → 2026-07-31

Core

Design, develop, and optimize biophysical assays (e.g., SPR, BLI) for characterization of small molecules and defining structure-activity relationships.

Role type

Principal Scientist, Biophysicist

Builds

Biophysical assays and screening workflows for drug discovery

Domain

Biophysics / Drug Discovery

Deliverable

production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work

Required skills

Biophysical assay design, SPR, BLI, structure-activity relationship analysis, laboratory automation, project management, data interpretation

Preferred skills

Post-doc experience, novel technology integration, electronic laboratory management systems, liquid handling systems

Technologies

SPR, BLI, laboratory automation platforms, liquid handling systems

Responsibilities

Design and optimize biophysical assays; execute routine assays for structure-activity relationships; implement automation solutions; collaborate on cross-functional projects; analyze and present scientific data; maintain laboratory records and contribute to publications

Seniority

Principal, hands-on IC with strategic oversight

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