Principal Scientist, Neuroscience / Genetic Medicine
Core
Design and lead preclinical experiments to evaluate efficacy, target engagement, and delivery efficiency of viral and non-viral genetic medicines for central nervous system disorders.
Role type
Principal Scientist, preclinical development
Builds
Preclinical data packages for genetic medicine candidates
Domain
Neuroscience / Genetic Medicine
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
DNA/RNA therapeutic evaluation in small-animal models, molecular biology techniques, team leadership, data interpretation, regulatory report authoring
Preferred skills
Ph.D. in neuroscience/gene therapy, 5+ years postdoc/industry experience in CNS drug discovery, knowledge of viral/non-viral delivery modalities
Technologies
AAV transgene cassettes, CNS disease models
Responsibilities
Design experiments for therapeutic candidates, lead associate teams, interpret complex datasets, communicate strategy to senior leaders, author preclinical study reports, mentor junior scientists
Seniority
Principal, hands-on IC with mentorship
