Senior Associate Scientist, R&D Chemistry
Core
Synthetic organic chemist supporting Regeneron's antibody-drug conjugate (ADC) drug discovery by designing and executing multistep syntheses for small-molecule payloads and linkers.
Role type
Senior Associate Scientist, R&D Chemistry (Synthetic Organic Chemist)
Builds
Novel small-molecule payloads and linkers for antibody-drug conjugate therapeutics
Domain
Biopharmaceuticals / Oncology / Metabolic Disease / Infectious Diseases
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
Retrosynthetic analysis, synthetic route design, multistep synthetic protocol execution, compound isolation and characterization, spectroscopic data interpretation, small-molecule synthetic organic chemistry, drug discovery processes
Preferred skills
Antibody-conjugate linker generation, peptidomimetics, biological target validation, ADME/PK, PD/efficacy
Technologies
N/A
Responsibilities
Perform laboratory activities for small-molecule syntheses, troubleshoot and analyze experimental data, discuss biological data to address structure-activity relationships, identify new synthetic strategies, participate in cross-functional meetings
Seniority
Senior, hands-on IC