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Senior Scientist, Molecular Discovery

USA - California - South San Francisco (Grand Ave)💼 Full-time💰 $131,400–$131,400🗓 2026-07-08 → 2026-07-30

Core

Design and execute molecular interaction assays using SPR and biosensor platforms to characterize proteins and antibodies for biologics discovery and lead optimization.

Role type

Senior Scientist, Biophysical Assay Development

Builds

High-quality kinetic and affinity data for candidate selection and optimization in a biologics pipeline

Domain

Biophysics, Protein Engineering, Drug Discovery

Deliverable

production ML models | product features | dashboards & analysis | research

Required skills

SPR/BLI assay development, experimental design, protein characterization, biophysical principles, data analysis, project management

Preferred skills

High-throughput/automated assay platforms, AI/ML-enabled protein engineering, complementary binding techniques (FACS, ITC, ELISA), cell-based assays

Technologies

Biacore, SPR, BLI, FACS, ITC, ELISA, Meso Scale Discovery

Responsibilities

Design and execute experiments to characterize molecular interactions; Develop and optimize assays across multiple binding formats; Partner with computational teams to support AI/ML-driven design workflows; Contribute data to candidate evaluation and optimization decisions; Explore new technologies to enhance assay throughput and data quality; Mentor junior scientists

Seniority

Senior, hands-on IC

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