Senior Laboratory Research Scientist
Core
Designing, expressing, and purifying proteins and complexes to build a scalable production pipeline for cryo-EM and AI-driven structural biology research.
Role type
Senior hands-on protein biochemist (structural biology)
Builds
Scalable protein production workflows and cryo-EM-ready samples for protein dynamics and drug discovery
Domain
Biomedical research / Structural biology / Protein biochemistry
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
protein expression, protein purification, protein quality control, in vitro binding assays, activity assays, workflow scalability design, automation integration
Preferred skills
automated liquid handling (Hamilton, Tecan, Beckman), high-throughput purification, plate-based workflow miniaturization, sample tracking/LIMS, Python scripting, biophysical assays (SPR, MST, TR-FRET, NanoBiT, mass photometry)
Technologies
cryo-EM, Hamilton, Tecan, Beckman, LIMS, Python
Responsibilities
Designing, cloning, expressing, and purifying proteins and protein complexes; Developing scalable protein production and purification workflows; Delivering high-quality, cryo-EM-ready samples; Performing protein quality control, binding, and activity assays; Designing workflows with automation and scalability in mind; Supporting implementation of automated liquid-handling technologies
Seniority
Senior, hands-on IC