Sr Scientist, Structural Chemistry
Core
Determine high-resolution structures of proteins and macromolecular complexes using cryo-EM and X-ray crystallography to support drug discovery.
Role type
Senior Scientist, Structural Chemistry
Builds
Structural insights integrated into medicinal chemistry and biologics design efforts
Domain
Biopharmaceuticals / Structural Biology
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
Cryo-EM workflows, X-ray crystallography, 3D reconstruction, model building, recombinant protein construct design, protein expression and purification
Preferred skills
Single-particle cryo-EM optimization, data acquisition, hit validation, hit-to-lead optimization
Technologies
Cryo-EM instrumentation, X-ray crystallography equipment
Responsibilities
Conduct cryo-EM workflows including grid preparation, data collection, image processing, and model building; Collaborate with cross-functional teams to integrate structural insights into drug design; Contribute to scientific publications and reports; Manage multiple projects independently
Seniority
Senior, hands-on IC