2027 Spring Co op Chemistry Lipidprotein Conjugation for Targeted LNPs Waltham MA
Core
Develop lipid-protein conjugation strategies for targeted lipid nanoparticles (LNPs) to enable cell- and tissue-specific mRNA delivery.
Role type
Chemistry co-op (Lipid-Protein Conjugation)
Builds
Novel Lipid-Protein Conjugates for Targeted LNPs
Domain
Biopharma / mRNA therapeutics / Nanomedicine
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
bioconjugation chemistries, organic synthesis, purification (dialysis, HPLC), characterization (HRMS, NMR, LCMS), in vitro/in vivo assay support, IP generation
Preferred skills
organic/bioconjugation chemistry experience, nanomedicine knowledge, mRNA biology knowledge
Technologies
NHS ester, maleimide, click chemistry, dialysis, prep HPLC, HRMS, NMR, LCMS
Responsibilities
Synthesize and purify lipid-protein conjugates, characterize synthesized conjugates, submit for in vitro/in vivo assays, maintain lab notebooks, collaborate with formulation and discovery biology teams
Seniority
Co-op, undergraduate/graduate student