Scientist
Core
Design and implement high-throughput cell-based assays and conduct molecular mechanism of action studies to identify and characterize drug candidates for targeted protein degradation.
Role type
Senior Scientist (Cell Biology/Drug Discovery)
Builds
Novel therapeutics for disease intervention via small molecule discovery
Domain
Biopharma / Targeted Protein Degradation
Deliverable
production ML models | product features | dashboards & analysis | research
Required skills
mammalian cell culture, multi-well plate-based cellular assays, immunoblotting, stable cell line generation, cellular transfection, basic molecular biology, high-throughput screening
Preferred skills
targeted protein degradation assays, automation instruments, multi-mode plate readers
Responsibilities
Design and implement high-throughput cell-based assays; Conduct small molecule mechanism of action studies; Generate and characterize stable cell lines; Perform routine culture, expansion, and maintenance of mammalian cell lines; Conduct molecular experiments including DNA/RNA/protein extraction and immunoprecipitation; Write protocols, procedures, and technical reports; Analyze and troubleshoot routine experimental problems
Seniority
Senior, hands-on IC