Senior Associate Scientist, Investigative Sciences
Core
Conduct in vitro and in vivo mechanistic studies to evaluate RNAi compounds and assess safety profiles using biochemistry and cell/molecular biology assays.
Role type
Senior Associate Scientist, Investigative Sciences
Builds
siRNA research data and safety profiles for RNAi therapeutics
Domain
Biotechnology / RNAi therapeutics
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
mammalian cell culture, molecular biology techniques, RNA/DNA/protein quantification, ELISA, RT-qPCR, cell-based assay development, fluorescence microscopy, data analysis (GraphPad Prism/FlowJo), experimental troubleshooting
Preferred skills
experience in oligonucleotides, lipid-based transfection, electroporation, high-content imaging
Technologies
GraphPad Prism, FlowJo, ELN
Responsibilities
Support investigative mechanistic siRNA research efforts; Maintain and manipulate diverse mammalian cell lines and primary cells; Develop, validate, and troubleshoot cell-based assays; Analyze complex datasets; Present experimental results to cross-functional teams
Seniority
Mid-level, hands-on IC