Scientist Nucleic Acids Computational Biology
Core
Design and implement computational approaches to uncover RNA structure–function relationships and support discovery of next-generation mRNA medicines.
Role type
Senior IC computational biologist (RNA/nucleic acids)
Builds
Custom mRNA optimization strategies and computational tools for high-throughput insights
Domain
Biopharmaceuticals / RNA therapeutics / Computational Biology
Deliverable
production ML models
Required skills
RNA biology, RNA secondary structure analysis, Python, R, cloud computing, high-performance computing, NGS data analysis, AI/ML modeling
Preferred skills
PhD in Computational Biology/Physics/CS, experience with diverse RNA sequencing modalities (ribosome profiling, CLIP-seq, single-cell RNA-seq), applying AI/ML to NGS datasets, computational modeling of nucleic acid functions
Technologies
Python, R, cloud platforms, HPC environments
Responsibilities
Build and implement custom mRNA optimization strategies to fine-tune expression, stability, and immunogenicity; Innovate on mRNA designs using scientific literature; Collaborate to generate and analyze NGS data from RNA structure probing experiments; Lead cross-functional collaboration to design studies and validate computational discoveries
Seniority
Senior, hands-on IC