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Senior Research Scientist

Wilmington, DE, US💼 Full-time🗓 2026-09-02 → 2026-09-26

Core

Design, express, purify, and characterize recombinant proteins and antibodies to support structural biology, drug discovery, and downstream applications.

Role type

Senior Research Scientist (Protein Chemistry & Biophysics)

Builds

High-quality protein and antibody samples for X-ray crystallography, cryo-EM, and functional assays

Domain

Biotechnology / Pharmaceutical Research / Structural Biology

Deliverable

production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work

Required skills

recombinant protein expression, protein purification (chromatography), biophysical characterization, antibody handling, data analysis, project management

Preferred skills

AI-enabled approaches to protein production, troubleshooting complex expression issues

Technologies

SEC-HPLC, DSF, BLI, SPR, SDS-PAGE, affinity chromatography, ion exchange, size-exclusion chromatography

Responsibilities

Design and optimize recombinant protein constructs; perform transfection and cell line maintenance; execute purification workflows; characterize proteins using analytical techniques; troubleshoot expression and stability challenges; support antibody discovery programs; manage multiple research projects independently

Seniority

Senior, hands-on IC

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