Senior Scientist, siRNA Screening Automation and Molecular Analytics
Core
Develop and operate high-throughput siRNA screening workflows using laboratory automation to accelerate lead discovery and optimization.
Role type
Senior Scientist, siRNA Screening Automation and Molecular Analytics
Builds
Robust, scalable siRNA screening workflows and data analysis pipelines for drug discovery.
Domain
Biotechnology / Pharmaceutical / siRNA therapeutics / Molecular Biology
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
laboratory automation, high-throughput screening workflows, coding for automation systems, RNA extraction, RT-qPCR assay development, NGS library construction, siRNA screening, oligonucleotide therapeutics, RNA biology, scripting, data processing tools
Preferred skills
siRNA screening, oligonucleotide therapeutics, RNA biology, NGS workflows integration with automation, platform buildout in matrixed drug discovery environment
Technologies
automated liquid-handling systems, RT-qPCR, RNA-seq, next-generation sequencing (NGS)
Responsibilities
Execute high-throughput siRNA screening workflows using automated liquid-handling systems; Develop and optimize automated methods for sample preparation including RNA extraction and RT-qPCR; Design and execute experiments to evaluate siRNA activity, potency, and selectivity; Establish and maintain data analysis workflows for screening datasets including assay QC and hit assessment; Drive development of NGS-based strategies using automation for gene expression profiling; Contribute to the improvement and standardization of screening workflows and automation procedures; Mentor junior scientists or research associates as needed.
Seniority
Senior, hands-on IC