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Senior Principal Scientist, Immune Cell Depletion Discovery Group, Immunology Discovery Research

Cambridge, MA, us💼 Full-time🗓 2026-06-16 → 2026-07-31

Core

Lead the Immune Cell Depletion Group to refine strategy and biology focus for next-generation therapies targeting rheumatological, dermatological, gastroenterological, and respiratory autoimmune diseases.

Role type

Senior Principal Scientist, Immune Cell Depletion Discovery

Builds

Preclinical drug discovery programs leveraging cellular depletion approaches

Domain

Immunology / Biopharmaceuticals

Deliverable

production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work

Required skills

Preclinical drug discovery program leadership, Cellular depletion approaches expertise, Immunology drug discovery, Managing and developing bench-based scientists, Experimental design and execution, GLP toxicology knowledge, Target discovery and validation

Preferred skills

Experience in autoimmune disease, Strong publication record, Leading early to late-stage discovery programs

Technologies

None explicitly stated

Responsibilities

Lead the Immune Cell Depletion Group within Immunology Discovery, Provide biology expertise to internal teams to advance next-generation therapies, Serve as a key member of the Immune Reset Therapeutics Discovery Leadership Team, Drive performance by leading from the bench to design and execute key experiments, Lead and influence early to late-stage discovery programs, Establish and manage external collaborations with leading research labs

Seniority

Principal, strategy & mentorship

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