Principal Research Scientist I, Novel Therapeutics
Core
Lead drug discovery programs to deplete pathogenic cells and enable long-term disease modification via cellular depletion modalities.
Role type
Principal Research Scientist I (Molecule Lead)
Builds
Novel therapeutics for serious and challenging diseases
Domain
Pharmaceutical / Immunology / Cellular Therapy
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
Cell depletion modality expertise, Drug discovery strategy, Experimental design, Risk assessment, Technical leadership, Scientific communication, Mentoring, Publication record, Patent record, Translational biology
Preferred skills
CAR-T/CAR-NK/CAR-Treg expertise, Complex antibody engineering (bispecific/novel formats)
Technologies
Cellular therapies, Antibody engineering
Responsibilities
Act as molecule lead on pipeline programmes, Develop and deliver drug discovery strategy, Serve as key lab focused scientist, Collaborate across immunology discovery and clinical development, Ensure high-quality project planning, Identify and evaluate emerging scientific trends, Mentor junior colleagues, Present scientific concepts to stakeholders
Seniority
Principal, hands-on IC with mentorship