Senior Principal Scientist, Cancer Immunology, Discovery Biology, Oncology Thematic Research Center
Core
Lead matrixed T cell engager (TCE) and cancer immunology discovery teams from target concept to IND, leveraging proprietary technologies to identify and validate novel therapeutic approaches for refractory tumors.
Role type
Senior Principal Scientist (Strategy & Mentorship)
Builds
Novel T cell engager and cancer immunology therapeutics
Domain
Oncology / Cancer Immunology / Drug Discovery
Required skills
T cell engager discovery, cancer immunology, IND development, in vitro experimentation, team leadership, strategic planning, cross-functional collaboration, complex biologics profiling, high throughput screening, in vivo functional assays
Preferred skills
T cell redirected therapies, discovery of T cell engagers, AI for strategic planning
Technologies
Proprietary technologies, in vitro models, in vivo models, ex-vivo models, biologically complex cell-based assays
Responsibilities
Lead matrixed TCE/cancer immunology discovery teams from concept to IND; Deploy techniques for function-based identification of lead drug candidates; Shape overall strategy and inform therapeutic innovation; Collaborate with functional area leads (pharmacology, DMPK, bioinformatics); Present complex concepts to governance and team meetings; Mentor junior scientists and lead lab-based in vitro biologists