Senior Principal Scientist, Cancer Immunology, Discovery Biology, Oncology Thematic Research Center
Core
Lead matrixed T cell engager (TCE) and cancer immunology discovery teams from target concept to IND, leveraging proprietary technologies to identify and validate novel therapeutic approaches for refractory tumors.
Role type
Senior Principal Scientist (Strategy & Leadership)
Builds
Novel T cell engager and cancer immunology therapeutics
Domain
Oncology / Cancer Immunology / Biologics
Required skills
T cell engager discovery, cancer immunology strategy, in vitro experimentation leadership, IND contribution, cross-functional program management, complex biologics profiling, high throughput screening, biologically complex cell-based assays, in vivo functional assay interpretation, AI for strategic planning
Preferred skills
T cell redirected therapies development, complex biologics discovery, matrixed discovery program leadership, mentoring lab-based biologists
Technologies
Proprietary T cell engager platforms, in vitro/ex vivo models, biologically complex cell-based assays
Responsibilities
Lead matrixed TCE/cancer immunology discovery teams from concept to IND; Deploy techniques for function-based identification of lead drug candidates; Shape overall strategy and inform therapeutic innovation; Collaborate with functional leads (pharmacology, DMPK, bioinformatics) to drive programs; Present complex concepts to governance and full team meetings; Mentor junior scientists and lead biology teams supporting in vitro experimentation
Seniority
Senior Principal, Strategy & Mentorship