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Senior Principal Scientist, Cancer Immunology, Discovery Biology, Oncology Thematic Research Center

Seattle 400 Dexter - WA - US💼 Full-time💰 $174,020–$174,020🗓 2026-07-01 → 2026-07-31

Core

Lead matrixed T cell engager (TCE) and cancer immunology discovery teams from target concept to IND, leveraging proprietary technologies to identify and validate novel therapeutic approaches for refractory tumors.

Role type

Senior Principal Scientist, Discovery Biology (Strategy & Leadership)

Builds

Novel T cell engager and cancer immunology therapeutics

Domain

Oncology / Cancer Immunology / Biologics

Deliverable

production ML models | product features | research | client delivery

Required skills

T cell engager discovery, cancer immunology, in vitro experimentation, IND contribution, team leadership, strategic planning, complex biologics profiling, high throughput screening, biologically complex cell-based assays, in vivo functional assay interpretation, cross-functional collaboration

Preferred skills

T cell redirected therapies, discovery of T cell engagers, leading teams for complex biologics, interpreting in vivo functional assays, leading matrixed discovery programs, leveraging AI for strategic planning

Technologies

Proprietary technologies for T cell engagers, in vitro models, in vivo models, ex-vivo models

Responsibilities

Lead matrixed TCE/cancer immunology discovery teams from concept to IND; Deploy techniques for function-based identification of lead drug candidates; Shape overall strategy and inform therapeutic innovation; Collaborate with functional area leads to drive programs; Present complex concepts to governance and teams; Mentor junior scientists and lead lab-based in vitro biologists

Seniority

Senior Principal, Strategy & Mentorship

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