CareerPlan

Scientific Associate Director, Oncology Research

US - California - South San FranciscoFull-time2026-10-29 → 2026-11-09

Core

Lead a portfolio of antibody-based large-molecule therapeutics (T-cell engagers and antibody-drug conjugates) for solid tumors, specifically pancreatic cancer, from discovery through development candidate nomination.

Role type

Senior IC scientific leader (oncology research)

Builds

First-in-class TCE and ADC therapies for solid tumors

Domain

Biotech / Oncology / Immunology

Required skills

oncology T-cell engager (TCE) program leadership, antibody-drug conjugate (ADC) program leadership, solid-tumor cell biology, translational biology, protein engineering, pharmacology, safety assessment, biomarker development, cross-functional team leadership, strategic portfolio management

Preferred skills

pancreatic cancer expertise, human cancer genetics, oncogenic signaling, tumor–immune biology, mechanisms of response and resistance, computational biology, AI/ML integration, external scientific collaboration

Technologies

T-cell engagers, antibody-drug conjugates, protein engineering tools, computational biology platforms, AI/ML tools

Responsibilities

Define and lead preclinical research strategies for TCE and ADC therapies; build and execute cell-surface target discovery and validation strategy for pancreatic cancer; lead integrated cross-functional research plans across tumor biology, target validation, and clinical development; lead and develop a team of lab-based scientists; shape Oncology Research strategy by identifying emerging trends and integrating enabling technologies; establish productive external scientific collaborations; communicate scientific strategy and evidence to senior management and external audiences

Seniority

Senior, hands-on IC with strategic leadership