Senior Scientist I- Translational Medicine- PKS, ADME
Core
Design, develop, and execute in-vitro ADME assays (metabolic stability, permeability) and build next-generation lab automation capabilities to support drug discovery and development projects.
Role type
Senior Scientist I, Translational Medicine (ADME/PKS)
Builds
High-quality study data for informed decision-making in early discovery and compound optimization
Domain
Pharmaceutical drug discovery, ADME/DMPK, laboratory automation
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
ADME/DMPK assay design and execution, metabolic stability and permeability testing, LCMS-MS/HRMS/ICP-MS bioanalysis, laboratory automation (liquid handling, multiplexing), AI-enabled analytics integration, method development for small/large molecules, instrumentation troubleshooting, project timeline and budget management
Preferred skills
Cell culture experience, experience in drug discovery/development labs or CRO/Pharma/Biotech, knowledge of bioanalytical/toxicology/biomarker disciplines
Technologies
LCMS-MS, HRMS, ICP-MS, liquid handling systems, AI-enabled analytics platforms
Responsibilities
Plan and execute ADME assays; interpret data to support compound selection; contribute to novel ADME methodologies; advance automation strategies; develop bio-analysis methods; troubleshoot instrumentation; manage study timelines and budgets; contribute to regulatory documents (IND, NDA)
Seniority
Senior, hands-on IC
