Associate Director, Discovery DMPK
Core
Lead peptide DMPK strategy and ADME study design for early-stage peptide drug discovery projects, guiding lead optimization and DC nomination.
Role type
Senior IC discovery DMPK scientist
Builds
Novel peptide therapeutics (Helicons™ class) for Wnt/β-catenin-driven diseases
Domain
Biopharmaceuticals / Peptide drug discovery / ADME
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
PK/PD modeling, drug transporter assessment, drug-drug interaction assessment, regulated bioanalysis, WinNonLin, R, CRO partner management, regulatory submission guidance (IND/IB)
Preferred skills
AI tool proficiency, small molecule ADME principles, antibody ADME principles
Technologies
WinNonLin, R
Responsibilities
Lead peptide DMPK strategy for discovery projects; Design and interpret in vitro and in vivo ADME studies; Integrate DMPK data with medicinal chemistry and pharmacology; Present DMPK strategy, data interpretations, and risk assessments to project teams and senior leadership
Seniority
Senior, hands-on IC
