Sr Associate Scientist, Biology
Core
Design, develop, and execute bioanalytical assays for large molecules and ADCs to support pharmacokinetic (PK) studies in drug discovery.
Role type
Sr. Associate Scientist, PK Bioanalysis
Builds
High-quality PK data for large molecules (monoclonal antibodies, peptides, biologics) and antibody-drug conjugates (ADCs)
Domain
Pharmaceutical R&D / Bioanalysis / Drug Discovery
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
ligand-binding assay development (ELISA, MSD, Gyrolab), in vivo PK study execution, data analysis and curve fitting (4PL/5PL), PK/ADME principles for biologics, biological matrix handling, experiment design, troubleshooting
Preferred skills
LC-MS/MS, in vitro high throughput screening, laboratory automation
Technologies
ELISA, MSD, Gyrolab, LC-MS/MS
Responsibilities
Design and execute bioanalytical assays for large molecules and ADCs; Perform ligand-binding assays in various biological matrices; Independently analyze and interpret experimental data; Troubleshoot assay performance issues; Manage PK sample analysis workflows; Collaborate with DMPK and biology teams; Prepare presentations and reports; Contribute to workflow automation
Seniority
Senior, hands-on IC
