Senior Scientist Neuroscience
Core
Lead R&D agenda for bioconjugates and targeted delivery technologies to enhance blood-brain-barrier (BBB) crossing for neuroscience and neurodegeneration indications.
Role type
Senior Scientist Neuroscience (Project Lead & Team Manager)
Builds
Protein conjugation technologies, linkers, payloads, and bioconjugates for CNS drug delivery
Domain
Life Sciences / Neuroscience / Bioconjugates / ADCs
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
BBB crossing mechanisms, receptor-mediated transport, protein engineering, bioconjugation strategies, in vitro/in vivo study design, project management, team supervision, patent writing, scientific communication
Preferred skills
Brain-targeting modalities (bispecific mAbs, shuttles), BBB models, transgenic mouse models, CNS drug delivery challenges, multicolor immunohistochemistry, bioanalytical methods (ELISA, UPLC-MS), chromatography (SEC, IEX, RP-UPLC)
Technologies
MS Office, GraphPad Prism, SciFinder, WIPO
Responsibilities
Evaluate transcytosis mechanisms and propose bioconjugation strategies; design and coordinate efficacy/PK/PD/brain exposure studies; lead projects with €200-500k budgets; supervise and develop 2-4 direct reports; manage external collaborations and partnerships; prepare patent filings and scientific manuscripts; present data at conferences and internal meetings
Seniority
Senior, hands-on IC with team leadership
