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Scientific Director, Computational Chemistry

US CA San Diego💼 Full-time💰 $218,200–$218,200🗓 2026-07-02 → 2026-07-31

Core

Develops and leads innovative computational strategies to accelerate drug discovery from early discovery through clinical candidate nomination, integrating molecular modeling, cheminformatics, and AI/ML to optimize therapeutics.

Role type

Senior IC Scientific Director, Computational Chemistry

Builds

Drug discovery programs for small molecules, biologics, peptides, and targeted protein degradation

Domain

Biopharmaceuticals / Computational Chemistry / Drug Discovery

Deliverable

production ML models | product features

Required skills

Molecular modeling, structure-based drug design, ligand-based design, cheminformatics, AI/ML for drug discovery, generative chemistry, predictive modeling, cloud computing, high-performance computing, workflow automation, strategic planning, team leadership, scientific publication, IP strategy

Preferred skills

CNS drug discovery experience, familiarity with neuroscience research, experience with Schrödinger/OpenEye/MOE platforms, experience with Knime or equivalent

Technologies

Schrödinger, OpenEye, MOE, Knime, cloud computing environments, high-performance computing environments

Responsibilities

Develops and enforces computational chemistry strategies; leads application of molecular modeling and AI/ML; partners with medicinal chemistry and data science teams; evaluates and communicates computational results; drives innovation in emerging technologies; establishes computational workflows; represents function in R&D governance; oversees external collaborations; contributes to IP and publications; selects and develops personnel.

Seniority

Senior, hands-on IC with leadership and mentorship responsibilities

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