Research Leader / Senior Research Investigator (Computational Drug Design), London
Core
Lead computational chemistry strategy and AI-first drug design programs from target selection to candidate nomination, partnering with ML scientists to enhance the AI platform.
Role type
Senior IC computational drug design lead (with optional people management)
Builds
Novel molecules and innovative medicines for treating devastating diseases
Domain
Biotech / Pharma / Computational Chemistry / Generative AI
Deliverable
production ML models
Required skills
Computational chemistry, Python scripting, machine learning, generative AI, virtual screening, lead optimisation, project leadership
Preferred skills
Large language models, fragment-based drug design, PROTACs, ADME/DMPK
Technologies
Python, REINVENT, cofolding, AI-powered ligand/pose scoring methods
Responsibilities
Apply AI-first approaches to execute drug design programs; Establish principles for embedding AI/ML into computational chemistry workflows; Provide strategic input to ML platform teams; Identify and validate therapeutic targets; Champion the drug discovery pipeline and oversee external collaborations
Seniority
Senior, hands-on IC (or Program Lead with team management)
