Research Leader / Senior Scientist (Computational Drug Design), Cambridge, MA
Core
Lead computational drug design programs at the intersection of computational chemistry and AI, guiding projects from initiation to clinical candidate selection.
Role type
Senior IC computational chemist (program lead or technical lead)
Builds
Novel molecules and drug candidates for therapeutic areas
Domain
Biotech / Pharma / Drug Discovery
Deliverable
production ML models | product features
Required skills
Computational chemistry, Python scripting, cheminformatics, project leadership, strategic thinking
Preferred skills
Generative AI/ML for drug design, fragment-based drug design, ADME/DMPK principles, CRO management
Technologies
Python, REINVENT, cofolding, AI-powered ligand/pose scoring
Responsibilities
Apply AI-first approaches to drug design programs, establish principles for embedding AI/ML into chemistry workflows, provide strategic input to ML platform teams, oversee external collaborations with CROs, prepare scientific proposals and reports
Seniority
Senior, hands-on IC with potential people management
