Computational Chemistry Principal Research Scientist (Computational Drug Design)
Core
Lead computational drug design initiatives for hit/lead identification and optimization using molecular modeling, cheminformatics, and AI-enabled methods.
Role type
Principal Research Scientist (Computational Chemistry)
Builds
Drug candidates and design hypotheses for discovery programs
Domain
Biotechnology / Computational Drug Design
Deliverable
production ML models | product features
Required skills
Computational chemistry, molecular modeling, cheminformatics, AI-enabled methods, structure-based drug design, Python programming, data analysis
Preferred skills
Beyond-rule-of-five modalities, strategic scientific leadership
Technologies
Commercial and open-source molecular modeling software
Responsibilities
Apply computational methods to accelerate drug candidate discovery; provide strategic scientific leadership across discovery programs; partner with medicinal chemists to generate design hypotheses; integrate structural, biological, and ADME/DMPK data; evaluate and advance AI-enabled approaches for molecular design; mentor junior scientists
Seniority
Principal, hands-on IC with strategic leadership
