Senior Clinical Lead, Early Clinical & Experimental Therapeutics
Core
Design and lead early clinical studies (First-in-Human, Phase 1/2a) for oncology assets including RAS pathway inhibitors, translating preclinical data into coherent development plans for solid tumors and hematologic malignancies.
Role type
Senior Clinical Lead, Early Clinical & Experimental Therapeutics
Builds
Early clinical development plans, protocols, and trial data for oncology assets
Domain
Oncology drug development / Translational Medicine
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
Early Phase 1/2a clinical trial oversight, translational medicine strategy, GCP practices, cross-functional team leadership, protocol design, dose escalation decision-making, regulatory submission authoring, stakeholder engagement
Preferred skills
Combination therapy experience, cytoplasmic signaling pathway expertise, late-phase clinical trial conduct, bench science background
Technologies
AI-driven research tools, digital tools for drug development
Responsibilities
Design and lead early clinical studies including First-in-Human and Proof-of-Mechanism trials; Drive translational strategy by integrating preclinical data and biomarker insights; Serve as Study Medical Manager overseeing study preparation, conduct, and safety monitoring; Lead cross-functional teams coordinating regulatory, safety, biostatistics, and clinical operations functions; Make front-line clinical decisions on protocol design and dose escalation; Author and review key clinical documents including protocols and clinical study reports; Engage with internal and external stakeholders including investigators and health authorities
Seniority
Senior, hands-on IC with strategic decision authority
