Principal Scientist I or II, PK Sciences Therapeutic Areas (Multiple Listings)
Core
Develop and implement translational or clinical pharmacology strategies to support late clinical development of new medicines, bridging drug discovery and clinical application.
Role type
Principal Scientist, Clinical Pharmacology / PK Sciences
Builds
Translational and clinical pharmacology strategies for small molecules, biologics, ADCs, radioligand, and cell therapies
Domain
Biopharmaceuticals / Clinical Pharmacology / Drug Development
Required skills
Clinical pharmacology, Drug metabolism, Pharmacokinetics (PK), PK/PD evaluation, Study design, Regulatory science, Project management, Cross-functional collaboration
Preferred skills
AI/ML approaches for data automation and predictive modeling, Lead role experience in ADME/DMPK
Technologies
Simulation Software, AI/ML tools
Responsibilities
Represent PK Sciences in project teams and interact with regulatory agencies; Develop dosing strategies and analyze PK/PD data; Author pharmacokinetic sections of IND/IMPDs and NDA/BLAs; Collaborate with clinicians and ADME/M&S teams to integrate insights into study design and decision-making.
Seniority
Principal, hands-on IC with strategic oversight