Principal Scientist I or II, PK Sciences Therapeutic Areas (Multiple Listings)
Core
Develop and implement translational or clinical pharmacology strategies to support late clinical development of new medicines, bridging drug discovery and clinical application.
Role type
Principal Scientist, Clinical Pharmacology / PK Sciences
Builds
Innovative medicines across oncology, immunology, cardiovascular, renal, metabolism, neuroscience, and global health therapeutic areas
Domain
Biopharmaceuticals / Clinical Pharmacology / Drug Development
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure
Required skills
Clinical pharmacology, Drug metabolism, Pharmacokinetics (PK), PK/PD evaluation, Study design, Regulatory science, Project management, Cross-functional collaboration, AI/ML fluency
Preferred skills
Experience in lead role overseeing ADME/DMPK project strategy, Hands-on project experience with AI/ML approaches
Technologies
Simulation Software, Enterprise AI/ML tools
Responsibilities
Represent PK Sciences in project teams and interact with regulatory agencies, Develop drug candidates across R&D continuum providing PK/DM input, Elucidate PK/PD relationships and develop dosing strategies, Execute clinical pharmacology strategies including study design and data analysis, Author pharmacokinetic sections of regulatory documents (IND/IMPDs/NDA/BLAs), Collaborate with clinicians to integrate insights into study design and decision-making
Seniority
Principal, hands-on IC with strategic oversight
