Associate Director, Process Development (Fermentation)
Core
Lead upstream/fermentation process development for E. coli-based production of recombinant enzymes, plasmids, and related biological starting materials.
Role type
Associate Director, Process Development (Fermentation)
Builds
Scalable microbial fermentation processes and cell banks for mRNA technology platforms.
Domain
Biopharma / Microbial Fermentation
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
E. coli physiology and fermentation engineering, high-cell-density fed-batch process development, media/feed design, induction strategy optimization, DOE and scale-down modeling, microbial cell banking strategy, online/inline process monitoring (off-gas, OUR/CER), technology transfer, CMC support
Preferred skills
GMP cell banking experience, defined/semi-defined media and advanced feeding strategies, PAT tools (Raman/NIR, soft sensors), downstream purification knowledge, regulatory interactions
Technologies
fed-batch fermentation, off-gas analytics, OUR/CER, Raman/NIR, soft sensors, chromatography, UF/DF
Responsibilities
Lead upstream/fermentation process development, manage team and define development strategies, optimize high-cell-density processes, apply data-driven approaches to improve yield and robustness, lead microbial cell banking strategy, partner with downstream and quality teams, support technology transfer and CMC documentation, mentor technical staff
Seniority
Senior, hands-on IC with team leadership
