Senior Scientist – Upstream Process Development (Temporary Maternity Cover)
Core
Hands-on scientific and technical delivery of upstream mammalian cell culture process development, optimization, scale-up, and technology transfer for biologics pipelines.
Role type
Senior Scientist (Upstream Process Development)
Builds
Biologics products via CHO-based cell culture processes
Domain
Biopharmaceuticals / Bioprocessing
Required skills
Mammalian cell culture (CHO), aseptic technique, bioreactor operation (bench-scale/high-throughput), Design of Experiments, statistical analysis, CMC documentation, scale-up, technology transfer
Preferred skills
Perfusion processes, media/feed development, systems biology, multi-omics, metabolic modelling, JMP/SIMCA/Python/MATLAB proficiency
Technologies
ambr250, stirred-tank bioreactors, cell bag bioreactors, JMP, SIMCA, Design-Expert, Python, MATLAB
Responsibilities
Plan and execute upstream process development studies; operate bioreactor platforms; analyze cell growth and productivity data; support scale-up and technology transfer; prepare regulatory-quality process documents; coordinate with cross-functional CMC teams.
Seniority
Senior, hands-on IC
