Head of Discovery
Core
Lead internal lab and experimental science for PROTAC/RIPTAC/MDG drug discovery pipeline from target nomination to development-candidate selection.
Role type
Head of Discovery (senior IC with company leadership)
Builds
PROTACs, RIPTACs, MGDs (induced proximity drugs)
Domain
Biotech / Structural Proteomics / Oncology
Required skills
drug discovery program leadership, assay design and validation, CRO management, IND-enabling study planning, hands-on bench science, compound series triage
Responsibilities
Drive discovery programs from target nomination through development-candidate selection and IND-enabling studies; Manage external CROs for in vivo efficacy, PK/PD, DMPK and IND-enabling studies; Run experiments and troubleshoot assays at the bench; Help steer company strategy and execution
Seniority
Senior, hands-on IC with company leadership