Senior Scientist - Oligonucleotide Synthesis
Core
Developing innovative products for manufacturing biological drugs by leading oligonucleotide synthesis workflows and method development.
Role type
Senior Scientist, Oligonucleotide Synthesis
Builds
Automated oligonucleotide synthesis workflows, analytical methods, and optimized synthesis processes for biological drug manufacturing.
Domain
Life Sciences / Biotechnology / Oligonucleotide Chemistry
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
phosphoramidite chemistry, solid support synthesis, automated synthesizer configuration, HPLC, LCMS, mass spectrometry, method validation, experimental planning, technical advisory
Preferred skills
design control experience, chromatography systems, UNICORN software
Technologies
HPLC, LCMS, mass spectrometer, automated oligonucleotide synthesizers, UNICORN software
Responsibilities
Lead and own automated oligonucleotide synthesis workflow including instrument configuration and troubleshooting; Develop analytical methods to characterize oligonucleotides; Lead method development, optimization, verification, and validation activities; Act as subject matter expert in oligonucleotide synthesis; Independently plan, execute, and document experimental work; Present results at project meetings and conferences; Act as technical advisor to commercial teams.
Seniority
Senior, hands-on IC